Microbubbles offers wide applications in the versatile field like biotechnology, as ultrasound agents and drug delivery agents. They have equal importance in the domain of wastewater treatment plants and other affiliated industries. This is the reason that study on its stability plays a pivotal role in finding out specific applications. Coating microbubbles with surfactants helps in increasing their lifetime. In current research, anionic surfactant Sodium Dodecyl Sulfate (SDS) is used to generate microbubbles and increase their stability. The measurement of stability of bubbles at different SDS concentration pointed out the importance of SDS concentration for generation of stable bubbles. The drainage curve method was employed for estimating the stability in current research. Furthermore, the introduction of silica nanoparticles on the microbubbles were also analyzed and optimum concentration of silica was found out for stable bubbles.