The separation and removal of lanthanides has become a critical task due to the increasing volume of radioactive waste liquids from nuclear facilities. In this study, a novel adsorbent for the efficient removal of europium (Eu) was developed based on solid-phase separation technology. The zirconium phosphorodiamidate-functionalized mesoporous silica (MCM-Zr-PDA) was synthesized by grafting zirconium organophosphate and Tris(2-aminoethyl) amine onto mesoporous silica with a high specific surface area via layer modification technology. The surface of the mesoporous silica contains abundant and homogeneously distributed hydroxyl functional groups, which facilitate the dispersion of claw-like amine groups anchored on phospholipid moieties, leading to significant adsorption of Eu(III). The structure of the MCM-Zr-PDA adsorbent was confirmed through various characterization techniques, including IR spectroscopy, thermogravimetric analysis, solid-state NMR, and X-ray diffraction. The adsorption mechanism of the MCM-Zr-PDA was investigated through pH-dependent, isothermal, and kinetic adsorption experiments. As shown in Fig. 1, the adsorbent exhibited optimal adsorption performance at pH = 4, and achieved the maximum adsorption capacity of 93.5% within 5 min toward Eu(III), possessing the performance of rapid adsorption (Fig. 2). The MCM-Zr-PDA adsorbent thus shows great promise as an efficient material for europium extraction under low acid conditions, exhibiting excellent selectivity and stability.