Metastasis
摘要
Metastatic bone tumors are more common than primary bone tumors, with bone metastasis ranking as the third most frequent site of metastasis following the lungs and liver. This condition is most commonly associated with prostate and breast cancer, contributing to up to 70% of skeletal metastases. The incidence of bone metastasis varies by tumor type, with breast and prostate cancers leading the list at 65–75%, followed by thyroid, lung, bladder, renal cell carcinoma, and melanoma. Notably, bone metastases tend to occur more frequently in the spine, followed by the proximal femur and humerus. These metastases can lead to various complications, including pain, fractures, impaired mobility, and other serious health issues.