This chapter investigates the promising role of ultrasound imaging in managing obstructive sleep apnea (OSA). OSA affects millions globally and is associated with severe health risks, yet conventional diagnostic techniques like polysomnography often fall short in identifying specific sites of airway obstruction. Ultrasound is a non-invasive, radiation-free, and cost-effective alternative that allows for real-time evaluation of upper airway structures such as the tongue and pharyngeal walls. Various ultrasound modalities, including amplitude mode (A-mode), brightness mode (B-mode), Doppler mode, backscatter ultrasound imaging, and elastography, enable detailed assessments of tissue morphology, vascularity, and stiffness, offering valuable insights into OSA’s pathophysiology. While advantages exist, challenges remain regarding user dependency and the need for standardized protocols. This chapter advocates for future research to enhance the diagnostic capabilities of ultrasound and its integration with other diagnostic modalities, paving the way for improved patient outcomes in OSA management.