Satellites in orbit encounter mechanical disturbances originating from crucial onboard equipment, including reaction wheels, inertial reference units and thrusters. To mitigate these disturbances, an active isolation system (AIS) is employed, typically comprising a passive mechanical isolator, sensors, actuators, and a digital controller. The effectiveness of the AIS heavily relies on the digital controller. This paper explores active vibration control techniques specifically designed for space-based applications. Additionally, a control simulation study is conducted on a smart flexible beam using a finite element-based state space approach for modeling. The performance evaluation considers metrics such as sum squared controller error and input performance. Popular controllers, including PID, LQG, Pole Placement Controller, and Model Predictive Control, are scrutinized.