The rise in terrorism has made the construction of blast-resistant structures imperative in developing countries. Blast load damage can result in building wall collapses, rubble spreading, and—most importantly—death. Compared to the design load, blast load is a dynamic load that is far more intense. The strategy for dealing with blast induced threats against structure requires attention during planning and design stage as later on it becomes challenging and impractical in construction industry to maintain National security. It will lead to well-designed structures having improved blast resistance and architecturally appealing appearance if blast response mitigation strategies can be incorporated into structure design at initial stage. The G + 6 structure is modeled and analyzed using STAAD PRO and ETAB, and blast loads are computed mathematically using IS 4991-1968: Criteria for blast resistant designs of structures for explosions above ground. Results from three different models i.e. conventional building, building with increased column and beam size and building with shear wall using both the software’s have been compared to find out most suitable blast resistant structure.