This chapter focuses on psychotherapy of substance and non-substance addiction (see Cognitive Behavioral Therapy in Chap. 16 ) and introduces the latest advances, mainly in mindfulness-based relapse prevention, therapy of pathological memory under in-depth hypnosis (TPMIH) and it further points out that the pathological memory, including “psychological craving,” at the level of implicit memory is practically the main root cause of the addiction disorder. The addiction disorder can be effectively repaired and eliminated through systematic and precise clinical psychological intervention. This chapter also introduces methods and progress of various types of substance and non-substance addiction.