South Asia is home to nearly half a billion women, where systemic gender disparities in education, employment, and healthcare persist. The region faces critical women’s health challenges, including high maternal mortality rates, widespread anemia, and mental health issues exacerbated by gender-based violence and migration-related stressors. Adolescent girls are particularly vulnerable, with high rates of child marriage, teenage pregnancies, and limited access to sexual and reproductive health services. Migration presents both opportunities and risks for women's health. While remittances can improve healthcare access and autonomy, female migrants often face socio-economic exploitation, mental health struggles, and barriers to access the services. Gender-sensitive policies, such as pre-departure training of the migrants, counselling of the migrant's left behinds and health insurance schemes, are essential to mitigate these risks. Addressing these issues this chapter, therefore, explores the quires of refugeehood and health vulnerabilities, enforcing laws against reproductive health matters, and psychological health among women in Global South. Prioritizing women's health is not only an ethical imperative but also a cornerstone for sustainable development in South Asia. Future efforts must focus on scalable interventions and robust data systems to track progress and ensure equitable outcomes.