Achieving efficient and clean combustion in gas turbine systems requires effective fuel–air mixing and flame stabilization, which can be enhanced through swirlers. This study focuses on a novel design combining a conical mixing tube with three strategically placed perforated meshes and a 3D-printed triple swirler burner (TSB) to improve uniform flow and compactness in gas turbine combustors. The perforated meshes allow for a shorter mixing tube while ensuring uniform flow distribution, which is crucial for optimal combustion. The mixing tube and TSB were tested in a vertical configuration using both experimental and numerical approaches at varying airflow rates. Stereo Particle Image Velocimetry (SPIV) was used to experimentally capture the flow field, while Computational Fluid Dynamics (CFD) simulations, utilizing Large Eddy Simulation (LES), provided a detailed analysis of the flow dynamics. The simulation results were validated against experimental data, showing close agreement. This integrated approach contributes to optimizing burner design for improved performance in gas turbine combustion systems.