This Paper has aimed to develop a sustainable domestic sewage treatment unit using Canna indica for treating kitchen wastewater from the college canteen. The treatment system included key components such as an oil and grease trap, anaerobic digester, aeration tank, and a constructed wetland planted with Canna indica. Initial parametric analysis showed that the levels of biochemical oxygen demand (BOD), chemical oxygen demand (COD), nitrogen, phosphorus, oil and grease, and TSS were above the permissible limits set by the CPCB, necessitating an effective treatment solution. After anaerobic digestion, BOD and COD levels reduced by 87.4% and 88.2%, respectively, while oil and grease were completely removed. After 24 h of retention in the Canna indica wetland, BOD and COD were reduced by 90% and 91.65%, respectively, and nitrogen removal reached 74.19%. After a 5-day retention period, the system achieved a 95% reduction in BOD, 93.89% reduction in COD, 96.59% reduction in nitrogen, and complete removal of TSS, phosphorus, and oil and grease. The synergistic action of Canna indica and the microbial consortium of Pseudomonas putida and Rhodobacter enhanced pollutant removal through phytoremediation, microbial degradation, and filtration. The results validate the system’s potential as an efficient, eco-friendly solution for domestic wastewater treatment, demonstrating consistent pollutant removal.