Landslides are the downslope fall of dislodged soil and rock debris under the force of gravity. It is one of the most frequently occurring and significantly damaging geo-environmental disasters in the world’s mountainous regions. It occurs due to the intricate relationships among climatic, geological, geomorphological, hydrological and human factors like LULC dynamics. Among these different factors, the impact of land use dynamics has been recognised as the most significant causes for the precipitation-triggered landslides throughout the globe. The occurrence of landslides is a primary geo-environmental distress in the parts of Darjeeling Himalayas, causing significant damage of lives and properties. The slope instability factors, along with the human interventions like clearing of forest cover for cultivation land and plantation, construction of roads in the steep slopes, expansion of settlements and construction of high-rise buildings, quarrying of stones from the steep slopes, etc., are some of the important reasons for recurrent landslide hazards in the region. This study attempts to generate the spatial landslide susceptibility zones of the river basin by analysing 18 landslide-causing factors in a GIS-based AHP (analytic hierarchy process) model. The production of the landslide susceptibility map would help to identify the vulnerable zones and minimise the effect through proper controlling methods. One of the mitigation measures can be an ecosystem-based approach. The ecosystem-based approach incorporates various measures like planting protective vegetative grasses, effective soil and water conservation methods, reforestation of barren lands and sustainable land use planning.