The wine production, included in the primary sector is a great cultural and economic deal, both nationally and internationally matters. However, it is highly dependent on natural resources, and traditionally involves high energy and water consumption. Given the global climate change scenario and the need for efficient resource management, it is necessary to implement a sustainable plan for the wine sector to realize sustainable practices. Data from the International Organization of Vine and Wine (OIV), states that global wine production exceeded 260 million hectoliters, in 2022. These has resulted in significant water and energy consumption, with around 500–1200 m3 of water used per hectare for irrigation and 1.2 gigajoules per hectoliter of wine produced, concluding that more than 80% of total water consumption is associated with irrigation, while more than 90% of energy consumption, is associated with winery processes. In this context, the scarcity of water or the need to achieve carbon neutrality by 2050 makes it essential to adopt energy and water efficiency measures that allow for the sustainable management of resources without endangering the sector’s viability. With this in mind, a case study applied to a Portuguese wine industry is presented, including data analysis from water and energy consumption. Also, efficiency metrics will be analyzed, proposing management and decision-support tools based on monitoring and sensor-based techniques. In fact, one example of these efficiency measures deals with the adoption of systems that provide real-time data on consumption patterns and resource availability in order to improve sustainability of the global process production.