Non-vascularized Fibular Grafts (NVFG) Enhanced Viability
摘要
Non-vascularized fibular grafts have been well known to bridge major bone defects of the extremities. However, we still lack knowledge about their incorporation to the host bone. The existing concept has been that majority of the transplanted cells in such grafts undergo necrosis and that almost all the new bone formation is generated from the host site. These grafts are known for their delayed rate of revascularization and remodelling. Vascular penetration of the graft by the host tissue only happens after resorption of the cortical surface by the osteoclasts (Lieberman and Friedlander 2005). These grafts are known to become radiolucent and significantly weaker than normal bone. This is known to last for months and depends on the graft size and implantation site of these grafts. However, the union of such grafts depends on the establishment of their blood supply. Non-union may also develop because of relative ischemia or lack of adequate immobilization.