Medicinal crops are a critical resource for humans and play an essential role in countering disease-causing pathogens. An effective approach to enhance the yield and quality of medicinal crops is through the application of mycorrhizae. These fungi form symbiotic partnerships with plant roots, enhancing nutrient and water absorption, bolstering plant disease resistance, and fostering overall soil health. By facilitating the mobilization of vital nutrients, such as phosphorus, which is often lacking in soils, mycorrhizae support better plant growth and help plants withstand various diseases and environmental stresses. In turn, this leads to healthier plants that produce higher quantities of bioactive compounds with medicinal potential. The use of mycorrhizal associations in medicinal crop cultivation provides a sustainable means to enhance both plant health and efficacy of medicinal products. Medicinal crops inoculated with mycorrhizal fungi generally exhibit increased biomass, superior secondary metabolite profiles, and higher overall yields than non-inoculated plants. By harnessing mycorrhizal symbiosis, it is possible to cultivate medicinal plants of higher quality, which holds significant promise in both the pharmaceutical and agricultural sectors. Despite this, our understanding of the potential application of mycorrhizal symbiosis in enhancing medicinal crop production remains limited. This review highlights the need for further investigation to elucidate the effects of mycorrhizal fungi on medicinal crops and devise effective strategies for their utilization in various agricultural settings.