Under the umbrella of education digitalization, the design and implementation of science education activities in kindergarten should approach life and intelligence. This study adopted a theoretical deduction method and evaluation research method to make use of digital intelligence technology to carry out theoretical research and practical exploration centering on life-oriented instructional design and implementation of science activities in kindergarten. Firstly, according to the rules of the scientific activities process as well as the characteristics of preschool children, the general process of preschool children’s scientific activities and the connotation of life-oriented preschool children’s scientific activities were clarified. Secondly, the content of the life-oriented instructional design of children’s scientific activities was sorted out, and the empowering role of digital intelligence technology in the life-oriented instructional design of children’s scientific activities was clarified. On this basis, the researchers constructed a LITD framework that emphasizes “Life-Oriented, Instructional Design and Technology-empowered” (LIDT), which is the instructional design for preschool children’s scientific activities empowered by digital intelligence technology. Finally, to facilitate practical application, a life-oriented implementation path for preschool children’s scientific activities empowered by digital intelligence technology was proposed. An empirical test was conducted through the scientific activity “AR Forest Adventure Tour” for a senior class of kindergarteners, and the effectiveness was analyzed and evaluated using a classroom teaching smart evaluation system. Relevant data indicated that this path could effectively enhance children’s scientific literacy, enrich children’s learning experiences, and develop children’s individual characteristics.