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Cancer immunotherapy offers a promising option to conventional cancer therapies, in this field, neoantigen detection is a rapidly evolving field; however, as it requires multiple bioinformatics stages, such as quality control, alignment, variant calling, annotation, and neoantigen prioritization. Each stage depends on specific software tools, which can create technical and compatibility challenges, often requiring significant expertise to integrate and manage. To address these challenges, we introduce NeoArgosTools, a novel flowchart-based platform, with an intuitive graphical interface, designed to simplify and streamline neoantigen detection pipelines in cancer immunotherapy research.

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NeoArgosTools: A Flowchart Pipeline Tool for Neoantigen Detection from Single Nucleotide Variants

  • 会议论文

  • 发表日期：

    2026年

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  • V. Machaca,
  • D. Lopez,
  • J. Mamani,
  • S. Ramos,
  • Y. Túpac

摘要

Cancer immunotherapy offers a promising option to conventional cancer therapies, in this field, neoantigen detection is a rapidly evolving field; however, as it requires multiple bioinformatics stages, such as quality control, alignment, variant calling, annotation, and neoantigen prioritization. Each stage depends on specific software tools, which can create technical and compatibility challenges, often requiring significant expertise to integrate and manage. To address these challenges, we introduce NeoArgosTools, a novel flowchart-based platform, with an intuitive graphical interface, designed to simplify and streamline neoantigen detection pipelines in cancer immunotherapy research.