Starting a family and becoming a parent are not without challenges, and the number of challenges is clearly increasing when one or both parents have a disability. In this narrative literature review, the most characteristic challenges of parents with blindness or visual impairment (BVI) and parents who are deaf or hard of hearing (DHH) are summarised, together with a brief look at the lived experience of their children. Independent of the type of disability, parents often experience that the professionals they meet along their parenting journey (e.g. medical staff, teachers) focus primarily on their disability and not on their role as parents. This negative attitude may hinder communication and may put the parent with disability in an unequal and inferior position to the professional, who may act as superior to the individual with a disability. Children of DHH parents and those of parents with BVI have unique challenges, but the parents agree that their children are more open to the needs of individuals with special needs and are more accepting towards any sort of human difference than their peers with non-disabled parents.