This empirical chapter examines Europe’s diverse approaches towards the Indo-Pacific region, clustered in three main groupings—the Big Four, Europe’s middle powers, and Europe’s minor powers—plus the EU. These clusters comprise 10 case studies: France, the UK, Germany, Italy, the Netherlands, Ireland, the Czech Republic, Lithuania, Sweden, and the EU. Through a novel examination, the chapter dissects the distinct trajectories pursued by these European actors in navigating the multifaceted Indo-Pacific landscape. It elucidates their engagement across trade, norms, and security, shedding light on the intricate dynamics shaping their interactions with regional stakeholders. Furthermore, the chapter critically evaluates the evolving geopolitical actorness of the EU within the Indo-Pacific arena, scrutinising its collective policies and institutional mechanisms. In doing so, it points to the different modes of European engagement—from bilateral and minilateral to multilateral. Lastly, it also explores select other European actors that, despite not possessing a regional policy or otherwise a noticeable Indo-Pacific engagement, display some potential for a growing regional interaction in the future. By providing the first comprehensive account of Europe’s Indo-Pacific approaches, this chapter aims to make an innovative contribution to the extant literature on both European foreign policy and the Indo-Pacific political, economic, and strategic landscape.