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Protein-based therapeutics, including monoclonal antibodies, cytokines, enzymes, and vaccines, have transformed the landscape of modern medicine, addressing previously untreatable diseases with high specificity and minimal off-target effects. Biologics constitute a rapidly expanding segment within the pharmaceutical market, propelled by progress in the fields of genetic engineering, engineered DNA technologies, and hybridoma approaches. Among the blockbuster protein therapies are adalimumab (Humira®) for autoimmune illnesses and trastuzumab (Herceptin®) for breast cancer (Walsh 2014; Strohl 2018).

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Solid-State Delivery and Stabilization of Therapeutic Proteins Using Freeze-Drying Technology

  • 章节

  • 发表日期：

    2025年

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  • Siva Venkata Reddy Devireddy,
  • Roshani Rajvansh,
  • Sara Fatima,
  • Kumar Nishchaya,
  • Himanshu Bansode

摘要

Protein-based therapeutics, including monoclonal antibodies, cytokines, enzymes, and vaccines, have transformed the landscape of modern medicine, addressing previously untreatable diseases with high specificity and minimal off-target effects. Biologics constitute a rapidly expanding segment within the pharmaceutical market, propelled by progress in the fields of genetic engineering, engineered DNA technologies, and hybridoma approaches. Among the blockbuster protein therapies are adalimumab (Humira®) for autoimmune illnesses and trastuzumab (Herceptin®) for breast cancer (Walsh 2014; Strohl 2018).