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Engaging in heavy physical labor at high altitudes may exacerbate lung injury. The study investigated the changes in pulmonary function and metabolic rate in acclimatized Han individuals in extremely high-altitude environments before and after handling and stacking. Six healthy male volunteers (age 21.7 ± 2.8 years) were recruited to transport five heavy objects (25 kg) for 3 meters and stack them. Pulmonary function parameters were collected by self-developed portable pulmonary function testing machine. Compared to pre-handling, the minute vetilation significantly increased by 8.47 L/min after handling (p = 0.015). There were no significant changes observed in tidal volume and breath rate. The PETCO2 decreased significantly at the end of 15 min of rest after handling (p = 0.01). Compared to pre-handling, metabolic rate significantly increased after handling (p = 0.014). Engaging in handling activities in high-altitude environments will increase the burden on the lungs and metabolic rate. Results have important implications in reducing lung injury caused by high-altitude heavy physical labor.

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Response of Pulmonary Function and Metabolic Rate After Heavy Object Handling at High Altitudes

  • 会议论文

  • 发表日期：

    2025年

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  • Chao Sun,
  • Shengjun Zhou,
  • Jie Chen,
  • Li Ding,
  • Yiyang Zhao,
  • Jiachen Nie,
  • Xiaojuan Bai

摘要

Engaging in heavy physical labor at high altitudes may exacerbate lung injury. The study investigated the changes in pulmonary function and metabolic rate in acclimatized Han individuals in extremely high-altitude environments before and after handling and stacking. Six healthy male volunteers (age 21.7 ± 2.8 years) were recruited to transport five heavy objects (25 kg) for 3 meters and stack them. Pulmonary function parameters were collected by self-developed portable pulmonary function testing machine. Compared to pre-handling, the minute vetilation significantly increased by 8.47 L/min after handling (p = 0.015). There were no significant changes observed in tidal volume and breath rate. The PETCO2 decreased significantly at the end of 15 min of rest after handling (p = 0.01). Compared to pre-handling, metabolic rate significantly increased after handling (p = 0.014). Engaging in handling activities in high-altitude environments will increase the burden on the lungs and metabolic rate. Results have important implications in reducing lung injury caused by high-altitude heavy physical labor.