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Acute respiratory distress syndrome (ARDS) is a severe condition characterized by diffuse alveolar damage, reduced lung compliance, and hypoxemia. Positive end-expiratory pressure (PEEP) is a crucial component of mechanical ventilation in ARDS, aiming to maintain alveolar recruitment, improve oxygenation, and prevent ventilator-induced lung injury. However, setting the appropriate PEEP level requires balancing the benefits of alveolar recruitment against the risks of overdistension and hemodynamic compromise [1, 2] [Ref: Algorithm 79.1].

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Approach to Setting PEEP in ARDS Patients in the ICU

  • 章节

  • 发表日期：

    2025年

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  • Shakti Bedanta Mishra,
  • Samir Samal,
  • Sagarika Panda

摘要

Acute respiratory distress syndrome (ARDS) is a severe condition characterized by diffuse alveolar damage, reduced lung compliance, and hypoxemia. Positive end-expiratory pressure (PEEP) is a crucial component of mechanical ventilation in ARDS, aiming to maintain alveolar recruitment, improve oxygenation, and prevent ventilator-induced lung injury. However, setting the appropriate PEEP level requires balancing the benefits of alveolar recruitment against the risks of overdistension and hemodynamic compromise [1, 2] [Ref: Algorithm 79.1].