Challenges and Possible Solutions to Contain AMR
摘要
Antimicrobial resistance (AMR) is one of the most significant global public health challenges, threatening the effective treatment of infectious diseases and endangering health, development, and economic stability. Despite increasing awareness, nations continue to encounter difficulties in establishing sustainable and coordinated strategies to manage AMR. The multifaceted nature of AMR obstructs its control. Political commitment is insufficient, with AMR frequently prioritised lower than other prominent health concerns. Limited and unsustainable financial resources undermine the execution of national action plans. Technical deficiencies, such as inadequate surveillance systems, poor diagnostic capabilities, and insufficient infection prevention and control measures, exacerbate the challenges. Programmatic issues, including inadequate integration across sectors, weak governance, and insufficient connections with preventive health initiatives, impede advancement. Regulatory deficiencies permit the overuse, misuse, and distribution of substandard antimicrobials, while a lack of educational programmes and professional training contributes to irrational prescribing practices. Weak multisectoral collaboration, underutilisation of community involvement, and insufficient engagement from the private sector further intensify the crisis. Innovation in research and development, combined with international collaboration, is essential for sustaining progress. To contain AMR, strong political will, adequate resources, effective governance, One Health collaboration, and community engagement are necessary to prevent a post-antibiotic era.