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Investigation of X-Ray Absorption Fine Structure and Antibacterial Activity of a Schiff Base-Dependent Cadmium Complex

  • Mayank Sharma,
  • Jitendra Tripathi,
  • Jaiveer Singh,
  • Karishma Tanwar

摘要

Cadmium complex coordinated with Schiff base ligand has a wide biological potential. The present work focuses on the Synthesis of Cadmium complex with Schiff base ligand in the ratio of 2:1 (ligand:metal), where the ligand was derived from 2-amino-3-methylbutanoic acid. The cadmium complex was examined by Cd K-edge XAFS spectroscopy using synchrotron radiation source at RRCAT, Indore, India. The XANES results confirm an octahedral coordination environment around the Cd ion in the +2 oxidation state. The experimental data were fitted with a theoretical model generated using FEFF calculations based on standard crystallographic parameters. The synthesized complex was tested for antibacterial activity against Staphylococcus aureus and E. coli using the well diffusion method. The observations provide insight into the antibacterial activity of the cadmium complex and suggest its potential for future applications.