Nanotheranostics in Personalized Veterinary Medicine
摘要
Nanotheranostics, a rapidly advancing field at the intersection of nanotechnology and theranostics, holds great promise for revolutionizing personalized veterinary medicine. The integration of nanoscale materials, imaging modalities, and therapeutic agents offers new opportunities for precise diagnosis, targeted treatment, and individualized care in animals. This abstract provides an overview of the applications, benefits, and challenges of nanotheranostics in personalized veterinary medicine. Nanotheranostic platforms can extend multi-arrayed benefits that include but not limited to improve animal production, reproductive performances, facilitates in stem cell therapy and regenerative medicine, veterinary transplant medicine, wildlife conservation, etc. In animal production, nanotheranostic platforms can facilitate comprehensive disease management by enhancing prophylactic, diagnostic and therapeutic interventions, nutritional enhancement, environmental monitoring, and animal welfare monitoring to optimize the output from animal husbandry. Towards improving reproductive performances of animals, nanotechnology can help in reproductive health evaluations, hormonal monitoring and management, genetic evaluation and selection, assisted reproductive technologies such as artificial insemination (AI), embryo transfer (ET), in vitro fertilization (IVF), or sex-sorted semen production, gamete quality improvement, etc. Nanotechnology in personalized veterinary medicine also facilitates in multiple aspects of stem cell therapy and regenerative medicine that include isolation and purification of stem cells, stem cell delivery and tracking, scaffold and matrix engineering, release of growth factors to maturation media, monitoring stem-cell therapy progress by theranostic imaging, etc. Transplant medicine is also an important domain where nanotechnology can deliver in terms of organ preservation, targeted drug delivery and immunomodulation, detection of rejection and complications, tissue engineering and regeneration, etc. Wildlife management and conservation is another area where nanotechnology can help in wildlife disease management, analysis of genetic diversity, physiological monitoring, animal movement monitoring and surveillance, nutritional management, monitoring environmental pollutants, and securing “One Health” perspective. Overall, nanotheranostics hold immense potential for personalized veterinary medicine, enabling precise diagnostics and targeted therapies in animals. By harnessing the power of nanotechnology, veterinarians can advance individualized care, improve treatment outcomes, and enhance the overall well-being of veterinary patients. Further research and collaborations are needed to overcome existing challenges and translate nanotheranostics into routine clinical practice in veterinary medicine.