The formation of nanomaterials that can fill new biomedical needs is urgently needed. High magnetic moments and high surface-to-volume ratios of magnetic nanoparticles (MNPs) make them desirable for targeted drug administration and hyperthermia therapy for cancer. They can also increase the sensitivity of biosensors and diagnostic equipment, act as contrast agents for magnetic resonance imaging (MRI), and perform other functions. The development of the following generation of MNPs, appropriate for these and other biomedical applications, is the product of recent advances in nanotechnology. The procedures used to form MNPs are covered in this chapter. A critical overview of recent developments in the application of MNPs for biosensing, MRI, drug release control, and hyperthermia therapy is also provided. Finally, difficulties encountered in the field and prospective uses of MNPs to enhance their properties are described.

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Current Challenges in Translating Magnetic Nanoparticles in Cancer Therapy Pros and Cons

  • Bhabani Shankar Nayak,
  • Preeti Budhlakoti,
  • Rekha Mehta,
  • Navin Chandra Pant,
  • M. Akiful Haque,
  • Swapna S.

摘要

The formation of nanomaterials that can fill new biomedical needs is urgently needed. High magnetic moments and high surface-to-volume ratios of magnetic nanoparticles (MNPs) make them desirable for targeted drug administration and hyperthermia therapy for cancer. They can also increase the sensitivity of biosensors and diagnostic equipment, act as contrast agents for magnetic resonance imaging (MRI), and perform other functions. The development of the following generation of MNPs, appropriate for these and other biomedical applications, is the product of recent advances in nanotechnology. The procedures used to form MNPs are covered in this chapter. A critical overview of recent developments in the application of MNPs for biosensing, MRI, drug release control, and hyperthermia therapy is also provided. Finally, difficulties encountered in the field and prospective uses of MNPs to enhance their properties are described.