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The present study keeps up with the modern scientific trend and recent advances in the valorisation of lignin—an aromatic heterobiopolymer with underestimated environmental, pharmaceutical, and biomedical potential, through the development of versatile hydrogels, nanoparticles, nanotubes, UV-protection materials, etc. In this respect, the recent approach utilizes the natural heterobiopolymer and biologically active compounds to synthesize innovative green lignin-based nanoparticles (LP) and flavonoid-loaded LPs and assesses their physicochemical properties, morphological characteristics, and antimicrobial potential. The nanoparticles were characterized and compared by X-ray diffraction (XRD), transmission electron microscopy (TEM), and Fourier-transform infrared spectroscopy (FTIR). The in vitro antibacterial potential of the LPs against Staphylococcus aureus pathogenic strain and the clinical isolate Bacillus cereus was evaluated.

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Sustainable Lignin Nanoparticles: A Versatile Proxy Agent with Advanced Environmental and Biomedical Significance

  • 会议论文

  • 发表日期：

    2025年

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  • Kamelia Petkova-Parlapanska,
  • Galina Nikolova,
  • Yanka Karamalakova,
  • Denitsa Nicheva,
  • Nikolina Rusenova,
  • Georgi Beev,
  • Ekaterina Georgieva,
  • Zhani Yanev,
  • Denitsa Georgieva,
  • Silviya Hristova,
  • Zvezdelina Yaneva

摘要

The present study keeps up with the modern scientific trend and recent advances in the valorisation of lignin—an aromatic heterobiopolymer with underestimated environmental, pharmaceutical, and biomedical potential, through the development of versatile hydrogels, nanoparticles, nanotubes, UV-protection materials, etc. In this respect, the recent approach utilizes the natural heterobiopolymer and biologically active compounds to synthesize innovative green lignin-based nanoparticles (LP) and flavonoid-loaded LPs and assesses their physicochemical properties, morphological characteristics, and antimicrobial potential. The nanoparticles were characterized and compared by X-ray diffraction (XRD), transmission electron microscopy (TEM), and Fourier-transform infrared spectroscopy (FTIR). The in vitro antibacterial potential of the LPs against Staphylococcus aureus pathogenic strain and the clinical isolate Bacillus cereus was evaluated.