Recent advancements in metal additive manufacturing allow to locally control the grain formation of the deposited material. With these new capabilities, different microstructures with specific material properties can be locally assigned to optimize structural part design and achieve economic savings. While there is already increasing interest and research in multi-material design of functional parts, the new possibilities of components with local material properties have yet to be fully explored. This research presents a concept for the automated design and validation of components with local material properties. A prototype of the concept is implemented and multi-material topology optimization and field-driven design are integrated as methods for the allocation of local material properties. The developed process chain is evaluated with two example geometries and challenges in the automation of the design process are discussed. The entire process, from microstructure allocation to geometry segmentation, numerical validation, and integration with the machine controller, is successfully automated, enabling a comprehensive exploration of potential optimization approaches.