Electrical processes on biological membranes are universally prevalent. They contribute to elementary functions of osmoregulation, metabolism, and exocytosis, and are of central importance for electrical signaling in neurons, sensory and muscle cells. In short: Without knowledge of electrophysiological mechanisms, numerous life processes (and their dysfunctions in diseases) cannot be understood.

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The History of the Patch Clamp Technique

  • Fabian Christoph Roth,
  • Markus Numberger,
  • Andreas Draguhn

摘要

Electrical processes on biological membranes are universally prevalent. They contribute to elementary functions of osmoregulation, metabolism, and exocytosis, and are of central importance for electrical signaling in neurons, sensory and muscle cells. In short: Without knowledge of electrophysiological mechanisms, numerous life processes (and their dysfunctions in diseases) cannot be understood.