This chapter weighs up the usefulness of the concept of intersectionality for research on women translators in history. It considers current scholarship on women in Early Modern England and argues that intersectionality is unlikely to offer conceptual or methodological advances and lead to new knowledge. The chapter identifies three major problems. First, intersectionality has evolved into a concept without a proper definition, and its original meaning has often been significantly distorted when applied to the pre-modern period. Second, there is no commonly agreed methodology for intersectional research, and scholars of Early Modern women writers/translators have so far struggled to develop robust and replicable research methods based on the concept. Third, embracing intersectionality may shift attention away from gender and undermine the feminist project. The article concludes by suggesting that a so-called ‘woman-interrogated’ approach to translation history would be more productive.