Vaccines have two types of protective effects, protective effects at subject level and protective effects at population level. The first effects are called direct vaccine effects, the second indirect vaccine effects. Direct vaccine effects are protective effects in vaccinated subjects that are due to the vaccination and that are absent in unvaccinated subjects. Indirect vaccine effects are protective effects in a population due to a high percentage of the population having been vaccinated.

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Vaccine Efficacy Trials

  • Jozef Nauta

摘要

Vaccines have two types of protective effects, protective effects at subject level and protective effects at population level. The first effects are called direct vaccine effects, the second indirect vaccine effects. Direct vaccine effects are protective effects in vaccinated subjects that are due to the vaccination and that are absent in unvaccinated subjects. Indirect vaccine effects are protective effects in a population due to a high percentage of the population having been vaccinated.