From Nail Bed Inflammation Straight to the Wheelchair—and When the Newborn No Longer Moves Its Leg

Within the last decades, the clinical picture of a septic arthritis and also bacterial osteomyelitis has changed, among other things because the spectrum of pathogens has changed. If one assumes a highly inflammatory process in the classic infection caused by Staphylococcus aureus or A-streptococci, then however, with gram-negative pathogens, especially with Kingella Kingae, a significantly more subtle clinical picture can be expected. In individual cases, the distinction from a basic rheumatological disease can be quite difficult, especially because the classic inflammation parameters ESR and CRP only inadequately represent the infection. Special pathogenesis factors such as, for example, a toxin formation of the pathogen or a special resistance situation are explained in the examples presented.