Motor vehicles already offer a high level of safety for occupants and for other road users (e.g., pedestrians and cyclists); further improvement presents the automotive industry with major challenges that can only be addressed by expanding the objectives and close cooperation between manufacturers, suppliers, and engineering service providers towards a common solution. While passive safety deals with accident consequence mitigating measures to limit the effects of accidents, active safety refers to the prevention of accidents and the reduction of their frequency. Integral safety now links both areas with the aim of further increasing the protection potential of all road users. In this context, the entire accident sequence from the accident’s origin, through the collision, to the rescue services is considered holistically, and protective measures are developed, tested, and implemented as standard in vehicles. The efforts of safety engineers aim to recognize dangerous situations during normal driving conditions early on, to interpret them, and consequently to initiate measures for accident prevention and to minimize the consequences of accidents. Assistance systems, conditionable and reversible occupant protection systems, or automatic emergency call systems, which will be discussed in more detail below, are already state of the art at many car manufacturers and are available to users of newer vehicles. Considered individually, these systems undoubtedly improve the potential for accident prevention. However, by using the information and data obtained with the help of the assistance systems, occupant protection systems can be activated early, even before the impact, if a collision appears unavoidable, so that the consequences of the accident can be reduced, or at least the accident severity can be reduced, leading to an improvement in vehicle safety. This linkage of active and passive safety over the pre-accident or pre-crash phase characterizes “integral safety”.