Compliance with future exhaust emission limits for commercial vehicle engines can only be achieved with additional heating systems and very complex, adapted exhaust gas aftertreatment systems. High additional fuel consumption is to be expected. The CatVap system is a new thermal management technology for exhaust gas aftertreatment systems, whose components can be heated up and kept on temperature levels efficiently and dynamically using this technology. It is characterized in particular by the ability to achieve very short heat-up times in the cold start phase and an efficient warm-up phase of the exhaust gas aftertreatment system. This makes it possible to significantly mitigate the conflict of objectives between nitrogen oxide reduction and fuel consumption in dynamic driving cycles. No further heating measures by the combustion engine are necessary. This paper shows “real drive emissions” from a commercial vehicle that demonstrate the high potential of CatVap as an additional heating system. It was successfully demonstrated that the trade of between low nitrogen oxide emissions and increased fuel consumption can be significantly softened. Through fuel-optimized engine operation and the use of a CatVap system, high nitrogen oxide conversion rates can be achieved—without additional fuel consumption. In tests on the engine test bench, it was also demonstrated that the heating measure can be operated with biofuels without adapting the hardware or software.