In times of social change, from Industry 4.0 to an Industry 5.0 and Society 5.0, the topics of product quality and safety are also strongly influenced. While the implementation of networked production and the Internet of Things through to the Internet of Production continues to progress, scientists from all disciplines are researching issues and solutions that a globally networked society poses. The following article is intended to provide an overview of where we currently stand from Industry 4.0 to Industry 5.0 and Society 5.0 and how this affects the various aspects of product quality and safety. Three different perspectives are taken into consideration. From an abstract meta-level point of view on technologies and industries, followed by a more concrete example of changes in companies. Eventually, the question of how a person’s individually perceived safety with regard to a product can be captured.