Introduction

The discovery of bioactive molecules originating from microorganisms has been the greatest medical advancement in history. Over 70% of all antibiotics in clinical use are derived from natural products produced by the bacterial group of actinomycetes (Bérdy, 2012; Newman & Cragg, 2012). Paul Ehrlich introduced the first antibiotic in 1910, an arsenic-based synthetic drug called “salvarsan” to treat syphilis (Hutchings et al., 2019).