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Iridoid glycosides, particularly prevalent in the Plantago genus, represent a notable category of secondary metabolites recognized for their interesting biological activities and functions in plant defense mechanisms. These compounds, including aucubin and catalpol, function as essential protective agents against environmental stress. Analytical techniques such as high-performance liquid chromatography have been essential in clarifying the profiles of these compounds among various Plantago species. Non-glycosidic iridoids and glycosidic iridoids are distributed in various Plantago species with skeletons made of either C9 or C10. Moreover, these compounds showed several biological effects such as antioxidant, anti-inflammatory, and anticancer effects. This chapter seeks to provide a thorough examination of the phytochemistry, biological activities, and metabolism related to iridoid glycosides in Plantago species, highlighting their importance and prospective therapeutic applications. The findings highlight the significance of these compounds in pharmaceutical research.

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Iridoid Glycosides of Plantago: Botany, Chemistry, Bioactivity, and Metabolism

  • 动态工具书词条

  • 发表日期：

    2025年

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  • Shaza H. Aly,
  • Amany A. Thabet,
  • Mohamed S. Abd El Hafeez,
  • Fatma A. Abdelbadie,
  • Esraa A. Elhawary,
  • Heba A. S. El-Nashar,
  • Mariam I. Gamal El-Din,
  • Mohamed El-Shazly

摘要

Iridoid glycosides, particularly prevalent in the Plantago genus, represent a notable category of secondary metabolites recognized for their interesting biological activities and functions in plant defense mechanisms. These compounds, including aucubin and catalpol, function as essential protective agents against environmental stress. Analytical techniques such as high-performance liquid chromatography have been essential in clarifying the profiles of these compounds among various Plantago species. Non-glycosidic iridoids and glycosidic iridoids are distributed in various Plantago species with skeletons made of either C9 or C10. Moreover, these compounds showed several biological effects such as antioxidant, anti-inflammatory, and anticancer effects. This chapter seeks to provide a thorough examination of the phytochemistry, biological activities, and metabolism related to iridoid glycosides in Plantago species, highlighting their importance and prospective therapeutic applications. The findings highlight the significance of these compounds in pharmaceutical research.