Charcot-Marie-Tooth Disease and Deafness

Charcot-Marie-Tooth disease (CMT) is the most common inherited neuromuscular disease (Morena et al. 2019), and among its various types, dysmyelinating and axonal types are the most common (Jani-Acsadi et al. 2015). The “Charcot-Marie-Tooth disease and deafness” is an autosomal dominant demyelinating motor and sensory neuropathy and a rare subtype of CMT1 called CMT1E. It contains 1–5% of all CMT1 cases (Li et al. 2013), and more than 40% of CMT1E patients have hearing loss (Jung et al. 2022).