Magnesium is a crucial cofactor for numerous enzymes, including all ATPase reactions involved in the biological functions of RNA and DNA. Magnesium plays a vital role in controlling neuromuscular function, cardiac rhythm, vascular tone, and hormone secretion (Touyz et al. 2024). In recent years, genetic forms of hypomagnesemia (HOMG) have been identified and categorized into HOMG Types 1–7, based on the underlying gene mutations that affect magnesium handling in the kidneys, intestines, or both. These types are often rare and hereditary, linked to mutations in specific genes responsible for magnesium transport. These mutations cause either renal magnesium wasting, decreased intestinal reabsorption or both.