The growing use of machine learning in healthcare requires careful consideration of patient privacy, particularly when models are trained on small medical datasets where the risk of re-identification is heightened. This study analyzes how regression models operate under privacy-preserving constraints and assesses their susceptibility to privacy leakage. A stability-based membership-inference framework quantifies how much model outputs reveal about individual training samples. Noise-injection techniques are applied to reduce this risk, and their effects on privacy and predictive accuracy are evaluated. Experiments on a small real-world medical dataset show a trade-off between model utility and privacy, identifying conditions in which regression models remain reliable while limiting exposure to membership-inference attacks.

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Evaluating Privacy Preservation in Regression Models for a Small Medical Dataset

  • Caroline König,
  • Pedro Jesús Copado,
  • Cecilio Angulo,
  • Àngela Nebot,
  • Alfredo Vellido

摘要

The growing use of machine learning in healthcare requires careful consideration of patient privacy, particularly when models are trained on small medical datasets where the risk of re-identification is heightened. This study analyzes how regression models operate under privacy-preserving constraints and assesses their susceptibility to privacy leakage. A stability-based membership-inference framework quantifies how much model outputs reveal about individual training samples. Noise-injection techniques are applied to reduce this risk, and their effects on privacy and predictive accuracy are evaluated. Experiments on a small real-world medical dataset show a trade-off between model utility and privacy, identifying conditions in which regression models remain reliable while limiting exposure to membership-inference attacks.