von Willebrand disease is the most common inherited bleeding disorder. The clinical presentation in affected individuals can range from very mild to severe bleeding symptoms, and it depends not only on the specific type of the disease but also on the individual bleeding phenotype. Gingival bleeding in people with von Willebrand disease has traditionally been seen as a sign of the underlying bleeding disorder. However, it is more often caused by poor oral hygiene and plaque-related gingivitis, which highlights the importance of maintaining good oral hygiene and implementing preventive dental care in these patients. Oral surgical procedures in patients with von Willebrand disease pose a significant risk of perioperative and postoperative bleeding. Therefore, dental practitioners must understand the causes and clinical features of this disorder, as well as proper preoperative management. This usually involves consulting with the patient’s physician or hematologist and, when necessary, administering desmopressin, von Willebrand factor concentrate, and antifibrinolytic agents. The use of local hemostatic measures is a vital part of preventing postoperative bleeding after oral surgical procedures.