This content offers an evaluation of research findings concerning the traits, synthesis, and use of metal chelate complexes. Moreover, this text describes the main ways in which metals take part in biological processes. The parameters influencing the process of metal ion binding with low-molecular-weight agents, including amino acids and macromolecules like polypeptides, are discussed. The rationale for applying polypeptides as carrier polymers in the development of bio metal preparations is outlined. The research into the materials with polymers containing metal atoms could be an interesting task. This is because research into biological activity prospects for these materials may lead to valuable data regarding the conformational peculiarities of metal complexes with polymers, and coordination phenomena for ions bound in these complexes. Thus, the study of the complexation process, not only for synthetic but also for natural polymers (polypeptides), covalently bound with macro- and microelements (metal ions), could be an interesting task. This research paper discusses the findings of a study on the poly complexes of different metal ions with polypeptides obtained from the alkaline hydrolysis of Bombyx mori silkworm cocoons using scanning electron spectroscopy. A potential way to do this is to carry out a thorough study using the techniques of polymer chemistry to study the process of complexation between the polypeptides obtained from the alkaline hydrolysis of the Bombyx Mori silkworm and metals like calcium, magnesium, and zinc. The long-term objective of this research is to synthesize novel drugs. Experiments have been carried out on living systems to study the pharmacological, biological, and specific features of the prepared polypeptide-metal complexes consisting of polypeptides and metals of the second group.