This chapter addresses two central and challenging questions at the intersection of social structure, culture, and politics. The first concerns the nexus between positions within the social structure and political choices, while the second examines the link between inequality and difference. Drawing on an extensive review of classical and contemporary contributions, from Karl Marx and Max Weber to Göran Therborn and Nancy Fraser, I argue that the relationship between the specific intersectional situation of individuals or groups and their cultural and political orientations is shaped by contingent articulations. Although intersectional positions impose clear constraints on cultural and political choices, the possible articulations between social positions and political-cultural choices remain multiple. Consequently, individuals and groups who, for instance, have experienced improvements in their positions within social hierarchies may or may not support the political forces associated with those changes. Ultimately, their political and cultural choices depend on how they assess their own intersectional situation.