Successful procurement of the abdominal organs for transplant is made possible by the combined efforts of donor medical centers, organ procurement organizations, surgical and anesthetic teams, and countless others. The two sources of deceased donor organs, donation after brain death and donation after cardiac death (DCD), are grounded in robust ethical and legal principles, and inform the mechanics, location, timing, and logistics of organ procurement. Medical management of the deceased organ donor is critical to successful procurement, for which a thorough understanding of the physiology of brain death is critical. Surgical procurement of the abdominal organs is a complex surgical procedure that aims to minimize warm ischemic time and preserve organ function to the maximum extent possible. Newer techniques, including normothermic regional perfusion, aim to increase the yield of DCD donation, while normothermic machine perfusion has both broadened access to extended criteria donors and allowed for the assessment of adequate organ function before implantation. Future efforts will undoubtedly continue to broaden access to transplant of the abdominal organs and allow for further growth of this life-saving therapy.

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Abdominal Organ Procurement: A Surgical Perspective for the Anesthesiologist

  • David A. Faber,
  • Steven C. Kim

摘要

Successful procurement of the abdominal organs for transplant is made possible by the combined efforts of donor medical centers, organ procurement organizations, surgical and anesthetic teams, and countless others. The two sources of deceased donor organs, donation after brain death and donation after cardiac death (DCD), are grounded in robust ethical and legal principles, and inform the mechanics, location, timing, and logistics of organ procurement. Medical management of the deceased organ donor is critical to successful procurement, for which a thorough understanding of the physiology of brain death is critical. Surgical procurement of the abdominal organs is a complex surgical procedure that aims to minimize warm ischemic time and preserve organ function to the maximum extent possible. Newer techniques, including normothermic regional perfusion, aim to increase the yield of DCD donation, while normothermic machine perfusion has both broadened access to extended criteria donors and allowed for the assessment of adequate organ function before implantation. Future efforts will undoubtedly continue to broaden access to transplant of the abdominal organs and allow for further growth of this life-saving therapy.