The management of chronic diseases is a major global challenge, especially regarding continuous monitoring and personalized care. In this context, bioengineering and telemedicine have emerged as key tools for remote patient monitoring, facilitating the efficient management of these conditions. This systematic review analyzes the impact and application of digital technologies in the monitoring of patients with chronic diseases. An analysis of 145 articles was conducted, of which 63 were selected for their relevance. The main findings highlight that digital health platforms, IoT devices, and video consultation platforms are the most widely used technologies in remote monitoring. The most monitored chronic diseases include chronic diseases in general, diabetes, and COPD. In terms of functionality, the applications focus mainly on telemonitoring and management, allowing for continuous and personalized patient follow-up. The results of this systematic review are useful for future research aimed at optimizing remote monitoring, improving the quality of care, and promoting smarter, more efficient, and sustainable health systems.