The demographic aging observed in Portugal has been accompanied by an increase in the prevalence of chronic diseases, functional dependence, and activity intolerance, especially in the elderly population. When associated with hospitalization, there is restricted mobility, contributing to a decline in functional capacity, with a negative impact on autonomy and quality of life. In this context, rehabilitation nursing plays a central role in promoting functionality and preventing loss of independence. This study describes the implementation of a structured rehabilitation nursing program aimed at people with activity intolerance in a hospital setting. The program included five elderly people and incorporated functional respiratory and motor reeducation interventions, including breathing exercises, aerobic and strength training, joint mobilization, training in activities of daily living, and energy conservation techniques. The evaluation was performed using standardized instruments, allowing for the analysis of the evolution of functional capacity, dyspnea, and muscle strength. The results showed a progressive and consistent improvement in activity tolerance and functional capacity in all participants, reinforcing the effectiveness of interventions by nurses specializing in rehabilitation nursing. These findings are consistent with current scientific evidence and support the relevance of individualized and early programs in addressing activity intolerance.