This chapter examines the retreat of glaciers in the Peruvian Andes and the adaptation strategies developed by Quechua women. It is based on an intersectional analysis that considers the vulnerabilities arising from gender, ethnicity and socio-economic conditions. The theoretical framework is rooted in political ecology and decolonial feminism, offering a lens through which to view these experiences within the context of a historical legacy of colonialism, mining extractivism and structural inequalities exacerbated by climate change. In this context, glacier loss, particularly in the Cordillera Blanca, compromises access to water and food security and threatens the cultural identity of Andean communities. As the primary bearers of reproductive work, women bear a disproportionate burden of the impacts generated by this crisis. In response, their adaptive strategies combine innovations in water management and community leadership with ancestral knowledge, shaping biocultural resilience forms that integrate indigenous knowledge and sustainable practices. However, the implementation of these strategies faces obstacles in the form of political resistance, financial barriers and cultural constraints that perpetuate the marginalisation of these women. To contextualise these findings more broadly, the chapter draws comparisons with cases from Guatemala and Brazil, identifying regional patterns of intersectional discrimination and contributing to the Latin American debate on climate justice. It proposes public policy guidelines that incorporate Indigenous epistemologies as a foundation for equitable and inclusive responses to the global environmental crisis.