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An increase of marrow mast cells together with plasma cells and lymphocytes has been observed in a variety of conditions: inflammations, wound and fracture healing, oedema and fibrosis (Fig. 76.1). Immunocytic and lymphocytic marrow infiltrations often have a high content of mast cells. Certain tumours may contain numerous mast cells. Mast cell proliferation on osseous surfaces is also a consequence of primary and secondary HPT. There is also a relation between mast cells and postmenopausal osteoporosis, suggesting that mast cells accelerate trabecular bone loss.

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Systemic Mastocytosis

  • 章节

  • 发表日期：

    2026年

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  • Reiner Bartl,
  • Christoph Bartl

摘要

An increase of marrow mast cells together with plasma cells and lymphocytes has been observed in a variety of conditions: inflammations, wound and fracture healing, oedema and fibrosis (Fig. 76.1). Immunocytic and lymphocytic marrow infiltrations often have a high content of mast cells. Certain tumours may contain numerous mast cells. Mast cell proliferation on osseous surfaces is also a consequence of primary and secondary HPT. There is also a relation between mast cells and postmenopausal osteoporosis, suggesting that mast cells accelerate trabecular bone loss.