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A critical global issue that must be addressed is the implementation of effective strategies for the management of agricultural waste, with a view to protecting the environment. It has been demonstrated that agricultural waste contains bioactive compounds, which have the potential to contribute to the development of biomaterials for wound healing applications. In this research, Pistacia vera (PV) waste extract—an agricultural by-product—was produced and characterized in combination with the polycaprolactone (PCL) biopolymer for use in wound dressing applications. In pursuit of this aim, the morphological, structural, mechanical, and antioxidant characteristics of the three dimensional printed (3DP) PCL/PV-based biocomposites were systematically investigated. Scanning electron microscopy (SEM) analysis revealed the presence of open and interconnected micropores. The molecular interactions between the components within the biocomposite dressings were demonstrated through Fourier-transform infrared spectroscopy (FTIR) analysis. The mechanical test results demonstrated that the fabricated wound dressings exhibited appropriate tensile strength values and were capable of withstanding relatively high levels of stress. Furthermore, the results of antioxidant assay tests demonstrated that the dressings exhibited significant free radical scavenging capacity. In conclusion, the tunable 3D-printed PCL/PV-based biocomposites demonstrate significant potential for use in the field of skin wound repair.

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Recycling of Agricultural Waste for Wound Healing: Effect of Bioactive Compounds Extracted from Plant on 3D-Printed Polycaprolactone-Based Dressings

  • 会议论文

  • 发表日期：

    2026年

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  • Sebahat Ozdemir,
  • Esranur Tan,
  • Nadide Seyhun,
  • Rasim Alper Oral,
  • Hayrunnisa Ozer,
  • Seyma Duman,
  • Busra Mutlu,
  • Fatma Demirci

摘要

A critical global issue that must be addressed is the implementation of effective strategies for the management of agricultural waste, with a view to protecting the environment. It has been demonstrated that agricultural waste contains bioactive compounds, which have the potential to contribute to the development of biomaterials for wound healing applications. In this research, Pistacia vera (PV) waste extract—an agricultural by-product—was produced and characterized in combination with the polycaprolactone (PCL) biopolymer for use in wound dressing applications. In pursuit of this aim, the morphological, structural, mechanical, and antioxidant characteristics of the three dimensional printed (3DP) PCL/PV-based biocomposites were systematically investigated. Scanning electron microscopy (SEM) analysis revealed the presence of open and interconnected micropores. The molecular interactions between the components within the biocomposite dressings were demonstrated through Fourier-transform infrared spectroscopy (FTIR) analysis. The mechanical test results demonstrated that the fabricated wound dressings exhibited appropriate tensile strength values and were capable of withstanding relatively high levels of stress. Furthermore, the results of antioxidant assay tests demonstrated that the dressings exhibited significant free radical scavenging capacity. In conclusion, the tunable 3D-printed PCL/PV-based biocomposites demonstrate significant potential for use in the field of skin wound repair.