Multifilament woven structures, made of warp and weft yarns with multiple textile strands, exhibit complex mechanical behavior due to their anisotropic nature. To accurately simulate the mechanical behavior of these woven fabrics, all fibers in the samples need to be modelled, with a special focus on contact friction interactions. Traditional methods often struggle to capture fiber and yarn interactions, making advanced computational modeling like multiscale modeling and finite element-based methods (FEM) essential for analyzing mechanical properties. This study examines the mechanical behavior of multifilament woven structures using a combination of numerical simulations and experimental analyses. The overall mechanical performance of the material is evaluated by integrating modeling techniques at the microscale, mesoscale, and macroscale levels. At the microscale, individual yarns are modeled to capture their distinct properties. At the mesoscale, a unit cell of plain-woven fabric is created to assess how the arrangement of yarns within the fabric affects the material’s overall mechanical behavior. Finally, the simulation advances to the macroscale, where the entire fabric structure is modeled. The numerical analysis was conducted using a finite element-based approach. Fiber and yarn geometries were measured using microscopy, and experimental tests were carried out to complement and validate the numerical models. The study revealed that the simulation model for the tensile behavior of multifilament and solid fibers exhibited deviations of 10% and 15.6%, respectively, compared to experimental results. Similarly, for fabrics, numerical simulations of tensile behavior showed discrepancies, with deviations of 14.1% at the meso-scale level and 20.7% at the macro-scale level. Despite these differences, a strong correlation between simulation and experimental data was observed. This research contributes to the advancement of predictive models capable of accurately simulating the real-world behavior of complex textile structures.