Hazard and Life Cycle Assessment of Safe and Sustainable Coatings
摘要
The PROPLANET project develops innovative bio-based coatings for textiles, food packaging machinery, and glass implementing a Safe and Sustainable by design (SSbD) approach to replace per- and polyfluoroalkyl substances (PFAS) compounds. A hazard assessment approach is carried out integrating a detailed toxicological in vitro assessment. Key toxicological endpoints, including cytotoxicity, genotoxicity, and pro-inflammatory responses are analysed in the chemicals formulations that replace PFAS-based coatings to ensure human health safety. Additionally, a Life Cycle Assessment (LCA) is conducted to evaluate the environmental impact of these formulations. Combining hazard assessment and LCA criteria enables the development and optimisation of coatings with low health and environmental risks. Furthermore, these assessments support PROPLANET’s PFAS-free coatings in meeting regulatory requirements and market demands by promoting safe, efficient, and eco-friendly solutions for industrial applications. The integration of these methodologies strengthens the transition toward safe and sustainable materials and products in a circular economy framework.